SCHEMBL728821

SCHEMBL728821

CCCCCC(CO)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
FDPS P14324 2/20 0.44
CYP2D6 P10635 2/20 0.42
SPHK1 Q9NYA1 1/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CETP P11597 1/20 0.42
HTT P42858 1/20 0.42
UBE2N P61088 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25350040 0.98 LMNA (0.54) LMNAFDPSCYP2D6SPHK1GMNN
SCHEMBL25215364 0.98 LMNA (0.54) LMNAFDPSCYP2D6SPHK1GMNN
SCHEMBL25221549 0.98 LMNA (0.54) LMNAFDPSCYP2D6SPHK1GMNN
SCHEMBL5680379 0.82 FDPS (0.48) LMNAFDPSSPHK1MAPTTSHR
SCHEMBL20222963 0.82 TSHR (0.50) LMNAALDH1A1TSHR
SCHEMBL27947143 0.82 FDPS (0.48) LMNAFDPSSPHK1MAPTTSHR
SCHEMBL19565241 0.82 FDPS (0.43) LMNAFDPSTSHRCA2OPRM1
SCHEMBL29344416 0.82 FDPS (0.48) LMNAFDPSSPHK1MAPTTSHR
SCHEMBL19123662 0.82 FDPS (0.48) LMNAFDPSSPHK1MAPTTSHR
SCHEMBL729105 0.82 LMNA (0.50) LMNAFDPSCYP2D6SPHK1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294048-B1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK ROEHM GMBH (DE) 2013-04-17 EP claimed
JP-2011526935-A 2011-10-20 JP claimed
EP-2294048-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS Evonik Röhm GmbH (DE) 2011-03-16 EP claimed
WO-2010003709-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK RÖHM GMBH (DE) 2010-01-14 WO claimed
EP-2675874-B1 METHOD OF LUBRICATING A DRIVELINE DEVICE LUBRIZOL CORP (US) 2019-04-10 EP disclosed
US-9540582-B2 Method of lubricating a driveline device THE LUBRIZOL CORPORATION (US) 2017-01-10 US disclosed
EP-2513270-B1 LUBRICATING COMPOSITION CONTAINING A NITRILE COMPOUND LUBRIZOL CORP (US) 2015-09-23 EP disclosed
EP-2467457-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2015-07-22 EP disclosed
EP-2891701-A1 Lubricating composition containing a corrosion inhibitor The Lubrizol Corporation (US) 2015-07-08 EP disclosed
EP-2891700-A1 Lubricating composition containing an antiwear agent The Lubrizol Corporation (US) 2015-07-08 EP disclosed
US-20150038385-A1 Method of Lubricating a Driveline Device THE LUBRIZOL CORPORATION (US) 2015-02-05 US disclosed
US-8946135-B2 Lubricating composition containing a nitrile compound THE LUBRIZOL CORPORATION (US) 2015-02-03 US disclosed
US-20110130590-A1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed
EP-2294048-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS Evonik Röhm GmbH (DE) 2011-03-16 EP disclosed
WO-2011022317-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT THE LUBRIZOL CORPORATION (US) 2011-02-24 WO disclosed
US-20100204509-A1 METHOD FOR PRODUCING (METH)ACRYLATES EVONIK ROEHM GMBH (DE) 2010-08-12 US disclosed
EP-2162423-A1 METHOD FOR PRODUCING (METH)ACRYLATES Evonik Röhm GmbH (DE) 2010-03-17 EP disclosed
WO-2010003709-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK RÖHM GMBH (DE) 2010-01-14 WO disclosed
WO-2009003744-A1 METHOD FOR PRODUCING (METH)ACRYLATES EVONIK RÖHM GMBH (DE) 2009-01-08 WO disclosed
US-20060135380-A1 Method of fatigue control THE LUBRIZOL CORPORATION 2006-06-22 US disclosed