Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.59 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408535 | 0.87 | KDM4E (1.00) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL7532494 | 0.87 | KDM4E (1.00) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| Acetic Acid SCHEMBL8948216 | 0.82 | KDM4E (0.80) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL7288245 | 0.81 | KDM4E (0.79) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL9332764 | 0.79 | KDM4E (0.76) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL2011932 | 0.79 | KDM4E (0.76) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL1738957 | 0.79 | KDM4E (0.76) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL2016180 | 0.79 | KDM4E (0.76) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL10611145 | 0.78 | KDM4E (0.68) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 | |
| SCHEMBL7298568 | 0.78 | KDM4E (0.61) | KDM4EL3MBTL1AOC3BCAT2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| CN-1091288-A | The oxytocin antagonist | OTSUKA PHARMA CO LTD (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |