Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL5569429 | 0.94 | SLC6A2 (0.56) | SCN1ASCN2ASCN3ALMNAHTT | |
| SCHEMBL3333232 | 0.87 | SCN1A (0.53) | SCN1ASCN2ASCN3ALMNAHTT | |
| Maleic Acid SCHEMBL9771017 | 0.86 | KDM4E (0.50) | ADRA1AKDM4EHTR1A | |
| SCHEMBL4667564 | 0.85 | SCN1A (0.65) | SCN1ASCN2ASCN3ALMNAHTT | |
| SCHEMBL5160316 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL14528133 | 0.84 | IDO1 (0.61) | SCN1ASCN2ASCN3ALMNAHTT | |
| SCHEMBL16767872 | 0.82 | HRH1 (0.48) | HRH1SLC6A4SLC6A3HTR2ACYP1A2 | |
| SCHEMBL10456715 | 0.82 | SCN1A (0.57) | SCN1ASCN2ASCN3ALMNAHTT | |
| SCHEMBL25375446 | 0.82 | CYP2D6 (0.68) | SCN1ASCN2ASCN3ALMNAHTT | |
| SCHEMBL4669231 | 0.81 | SLC6A2 (0.61) | SCN1ASCN2ASCN3ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672678-B1 | Azapeptide derivative | FUJIREBIO KK (JP) | 2000-10-25 | — | — | EP | claimed |
| US-5837687-A | BRONCHODILATORS, ANTIHISTAMINES AND ANTIINFLAMMATORY AGENTS; ASTHMA; ANTAGONIST OF NEUROKININ RECEPTORS | FUJIREBIO INC. (JP) | 1998-11-17 | — | — | US | claimed |
| EP-0672678-A1 | Azapeptide derivative | FUJIREBIO Inc. (JP) | 1995-09-20 | — | — | EP | claimed |
| WO-2022257981-A1 | USE OF COMPOUNDS IN INHIBITING OR KILLING MITES AND TREATING DRY-EYE SYNDROME | 广州岐微生物医药科技有限公司 | 2022-12-15 | — | — | WO | disclosed |
| EP-2500039-A1 | Oligomer-antihistamine conjugates | Nektar Therapeutics (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2008112257-A1 | OLIGOMER-ANTIHISTAMINE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
| US-7268166-B2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268166-B2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| EP-0672678-B1 | Azapeptide derivative | FUJIREBIO KK (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5837687-A | BRONCHODILATORS, ANTIHISTAMINES AND ANTIINFLAMMATORY AGENTS; ASTHMA; ANTAGONIST OF NEUROKININ RECEPTORS | FUJIREBIO INC. (JP) | 1998-11-17 | — | — | US | disclosed |
| EP-0672678-A1 | Azapeptide derivative | FUJIREBIO Inc. (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5162537-A | To safen acetamide herbicids used to control grassy and broadleaf weeds in rice, sorghum and wheat | MONSANTO COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4912119-A | Cardiovascular disorders | HEUMANN PHARMA GMBH & CO. (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0262448-A1 | Imidazolylguanidine derivatives, process for their preparation and medicines containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-04-06 | — | — | EP | disclosed |
| US-4049825-A | Aminoalkylethers; composition and method of use | GIST-BROCADES N.V. (NL) | 1977-09-20 | — | — | US | disclosed |
| US-4003932-A | DOPAMINERGIC PROPERTIES | GIST-BROCADES N.V. (NL) | 1977-01-18 | — | — | US | disclosed |