Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049655 | 0.83 | ALDH1A1 (0.61) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL5533637 | 0.83 | ALDH1A1 (0.61) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL4150403 | 0.82 | USP2 (0.57) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL4489543 | 0.82 | USP2 (0.57) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL4637391 | 0.81 | ANPEP (0.52) | ANPEPALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7979638 | 0.80 | ALDH1A1 (0.68) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL2179400 | 0.80 | KDM4E (0.52) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL6754051 | 0.79 | ANPEP (0.51) | ANPEPKDM4EUSP2ALDH1A1HSD17B10 | |
| SCHEMBL15876288 | 0.78 | GAA (0.40) | KDM4EUSP2ALDH1A1TSHRMEN1 | |
| SCHEMBL2201068 | 0.77 | GAA (0.57) | ANPEPKDM4EALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |