Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300289 | 0.84 | MAPT (0.62) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7297699 | 0.81 | MEN1 (0.61) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11357236 | 0.78 | KMT2A (0.51) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL9445665 | 0.78 | L3MBTL1 (0.74) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL8127190 | 0.75 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL30117933 | 0.74 | KMT2A (0.77) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL15437984 | 0.74 | KMT2A (0.77) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL10750201 | 0.74 | KMT2A (0.77) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL9370024 | 0.74 | KMT2A (0.77) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL8636891 | 0.73 | NPC1 (0.64) | KMT2AMEN1L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |