Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281969 | 0.89 | MAPT (0.43) | MAPTTP53SLC2A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9748563 | 0.85 | CYP3A4 (0.44) | MAPTCYP3A4 | |
| Fumaric Acid SCHEMBL9747735 | 0.85 | CYP3A4 (0.44) | MAPTTP53CYP3A4SLC2A1MEN1 | |
| Fumaric Acid SCHEMBL9747747 | 0.85 | CYP3A4 (0.44) | MAPTTP53CYP3A4SLC2A1MEN1 | |
| SCHEMBL7290621 | 0.81 | MEN1 (0.50) | MAPTTP53SLC2A1MEN1KMT2A | |
| SCHEMBL7278961 | 0.81 | CACNA1S (0.52) | MAPTTP53CYP3A4MEN1KMT2A | |
| SCHEMBL7280870 | 0.80 | PTPN1 (0.42) | MAPTTP53SLC2A1MEN1KMT2A | |
| SCHEMBL7292897 | 0.78 | CACNA1S (0.53) | MAPTTP53CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7300372 | 0.77 | MEN1 (0.41) | MEN1KMT2AALDH1A1POLBMAPK1 | |
| SCHEMBL7282106 | 0.77 | SLC2A1 (0.47) | MAPTTP53SLC2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | claimed |
| EP-0116368-A1 | Benzothiazine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-22 | — | — | EP | claimed |
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0116368-A1 | Benzothiazine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-22 | — | — | EP | disclosed |