Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281969 | 0.79 | MAPT (0.43) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL21246970 | 0.77 | RAB9A (0.65) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7288844 | 0.77 | MAPT (0.41) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7280870 | 0.77 | PTPN1 (0.42) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL9748612 | 0.75 | RAB9A (0.42) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL7292068 | 0.74 | HTR1A (0.46) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL7288638 | 0.71 | PDPK1 (0.44) | MEN1KMT2AHTTLMNAMAPK1 | |
| SCHEMBL7327312 | 0.70 | HSD17B10 (0.73) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5020108 | 0.70 | HSD17B10 (0.73) | SLC2A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7348790 | 0.70 | HSD17B10 (0.73) | SLC2A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237573-B1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4786635-A | THERAPEUTIC AGENTS FOR CIRCULATORY DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0237573-A1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0116368-A1 | Benzothiazine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-22 | — | — | EP | disclosed |