Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281969 | 0.83 | MAPT (0.43) | MAPTSLC2A1MEN1KMT2APOLB | |
| SCHEMBL7288844 | 0.80 | MAPT (0.41) | PTPN1MAPTSLC2A1MEN1KMT2A | |
| SCHEMBL7278811 | 0.80 | PTPN1 (0.41) | PTPN1MAPTPOLBLMNAALDH1A1 | |
| SCHEMBL7282106 | 0.77 | SLC2A1 (0.47) | MAPTSLC2A1MEN1KMT2APOLB | |
| SCHEMBL7288807 | 0.75 | POLB (0.42) | PTPN1MAPTMEN1KMT2APOLB | |
| SCHEMBL7292068 | 0.75 | HTR1A (0.46) | MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9748563 | 0.74 | CYP3A4 (0.44) | MAPT | |
| Hydrochloric Acid SCHEMBL7300372 | 0.73 | MEN1 (0.41) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| Fumaric Acid SCHEMBL9747747 | 0.72 | CYP3A4 (0.44) | MAPTSLC2A1MEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL9747735 | 0.72 | CYP3A4 (0.44) | MAPTSLC2A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0116368-A1 | Benzothiazine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-22 | — | — | EP | disclosed |