Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355337 | 0.94 | DAGLA (0.51) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7289513 | 0.94 | DAGLA (0.51) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7296896 | 0.91 | DAGLA (0.43) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7288980 | 0.89 | DAGLA (0.47) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7289503 | 0.86 | DAGLA (0.51) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7355327 | 0.86 | DAGLA (0.51) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7296891 | 0.85 | DAGLA (0.43) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7297473 | 0.85 | DAGLA (0.39) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7297464 | 0.82 | DAGLA (0.39) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B | |
| SCHEMBL7352247 | 0.77 | MPO (0.40) | DAGLANAMPTKDM4ESMN1; SMN2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |