Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352240 | 0.90 | MPO (0.38) | MPOSMN1; SMN2KDM4EKDM4CDAGLA | |
| SCHEMBL7297473 | 0.82 | DAGLA (0.39) | MPOSMN1; SMN2KDM4EDAGLANAMPT | |
| SCHEMBL7296896 | 0.79 | DAGLA (0.43) | MPOSMN1; SMN2KDM4EDAGLANAMPT | |
| SCHEMBL7297464 | 0.79 | DAGLA (0.39) | MPOSMN1; SMN2KDM4EDAGLANAMPT | |
| SCHEMBL7288983 | 0.77 | DAGLA (0.47) | MPOSMN1; SMN2KDM4EDAGLANAMPT | |
| SCHEMBL7296891 | 0.76 | DAGLA (0.43) | MPOSMN1; SMN2KDM4EDAGLANAMPT | |
| SCHEMBL7297341 | 0.76 | DAO (0.39) | MPOSMN1; SMN2KDM4ENAMPTKDM5A | |
| SCHEMBL7359592 | 0.76 | DAGLA (0.35) | MPOSMN1; SMN2KDM4EKDM4CDAGLA | |
| SCHEMBL7359581 | 0.76 | DAGLA (0.35) | MPOSMN1; SMN2KDM4EKDM4CDAGLA | |
| SCHEMBL7355337 | 0.75 | DAGLA (0.51) | SMN1; SMN2KDM4EDAGLANAMPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |