⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28043541 | 0.94 | — | — | |
| Ethoxycarbonyl Group SCHEMBL3225173 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL453 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5306888 | 0.90 | ALDH1A1 (0.38) | — | |
| Benzene SCHEMBL28953747 | 0.89 | MEN1 (0.31) | — | |
| Ethoxycarbonyl Group SCHEMBL27878173 | 0.88 | — | — | |
| Ethoxycarbonyl Group SCHEMBL728941 | 0.88 | — | — | |
| Ethoxycarbonyl Group SCHEMBL1653351 | 0.87 | — | — | |
| Ethoxycarbonyl Group SCHEMBL3767822 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022151732-A1 | PREPARATION METHOD FOR MIDAZOLAM HYDROCHLORIDE CRYSTAL FORM F AND USE THEREOF | 福安药业集团重庆礼邦药物开发有限公司 | 2022-07-21 | — | — | WO | claimed |
| CN-101156893-A | Mass control method of apricot red injection | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2008-04-09 | — | — | CN | claimed |
| EP-0259617-B1 | PROCESS AND PREPARATION FOR INACTIVATING VIRUSES | CHIMICASA GMBH (CH) | 1992-03-04 | — | — | EP | claimed |
| CN-115611815-A | Synthesis method of cytosine | 新乡瑞诺药业有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-110003076-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-105452220-B | Sulfamoyl pyrrole amide derivative and application thereof as medicine for treating hepatitis B | 爱尔兰詹森科学公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-107820496-A | For treating and preventing the hepatitis b virus infected new formic acid derivates of 4 oxo pyridine of Fourth Ring 3 | 豪夫迈·罗氏有限公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-103933430-B | Chronic hepatitis B medicine and preparation method thereof | 吴侠 | 2016-11-23 | — | — | CN | disclosed |
| CN-106146304-A | The method producing Ethyl formate | 山西同济药业有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-105816662-A | Traditional Chinese medicine for treating cardiovascular and cerebravascular diseases and preparing method of traditional Chinese medicine | 鲍洪升 | 2016-08-03 | — | — | CN | disclosed |
| CN-1799605-A | Pulse activating infusion and preparation method thereof | ZHEJIANG JINGXIN PHARMACEUTICA (CN) | 2006-07-12 | — | — | CN | disclosed |
| EP-0002327-B1 | PHARMACOLOGICALLY ACTIVE 6-LOWER ALKYL-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, METHOD OF PREPARING THEM AND INTERMEDIATES | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-04 | — | — | EP | disclosed |
| US-4342686-A | Intermediates for preparing 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| US-4265889-A | DOPAMINERGIC, HYPOTENSIVE | SMITHKLINE CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0002327-A1 | Pharmacologically active 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, method of preparing them and intermediates | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-13 | — | — | EP | disclosed |