Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290701 | 0.90 | TAAR1 (0.54) | TAAR1HTR1AHDAC8HDAC3HDAC4 | |
| SCHEMBL7300488 | 0.82 | TAAR1 (0.51) | TAAR1HTR1AHDAC8HDAC3HDAC4 | |
| SCHEMBL9401824 | 0.78 | TAAR1 (0.57) | TAAR1HTR1AHDAC8HDAC3HDAC4 | |
| SCHEMBL13372830 | 0.76 | TAAR1 (0.80) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9401700 | 0.76 | TAAR1 (0.55) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL9507338 | 0.76 | TAAR1 (0.55) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL7299851 | 0.76 | TAAR1 (0.62) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL7292001 | 0.75 | TAAR1 (0.50) | TAAR1HTR1AHDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7266355 | 0.75 | TBXAS1 (0.54) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL7293554 | 0.75 | TAAR1 (0.57) | TAAR1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |