Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683047 | 0.89 | TP53 (0.57) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL3684567 | 0.87 | SMPD1 (0.57) | THRATSHRPLA2G4BTHRB | |
| SCHEMBL3067042 | 0.86 | RARB (0.60) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL7271786 | 0.86 | TP53 (0.53) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL7280580 | 0.86 | RARB (0.60) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL878923 | 0.85 | HPGD (0.52) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL19750764 | 0.83 | PLA2G2A (0.51) | THRATP53TSHRPLA2G4BTHRB | |
| SCHEMBL7273154 | 0.81 | THRA (0.55) | THRATSHRPLA2G4BTHRB | |
| SCHEMBL3683009 | 0.80 | SMN1; SMN2 (0.55) | TSHRTHRB | |
| SCHEMBL7272065 | 0.80 | RARB (0.55) | TP53TSHRPLA2G4BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644199-B1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5693750-A | MICROBIOCIDAL ACTION AGAINST PNEUMOCYSTIS INFECTIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5569646-A | TREATMENT OF PNEUMONIA; MICROBIOCIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| EP-0644199-A1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |