Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290561 | 0.80 | DYRK1A (0.37) | ALDH1A1TP53CYP3A4ALOX15TDP1 | |
| SCHEMBL7291525 | 0.80 | KDM4E (0.35) | ALDH1A1MAPTMAOBKMT2AGAA | |
| SCHEMBL7278918 | 0.76 | ALDH1A1 (0.40) | HTTALDH1A1MAPTSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL7290643 | 0.75 | ALDH1A1 (0.40) | HTTALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7288895 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL7269116 | 0.69 | ALDH1A1 (0.44) | HTTALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7282398 | 0.69 | HTR2A (0.36) | ALDH1A1MAPTSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL7290637 | 0.68 | HTR2A (0.41) | HTTALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL7291307 | 0.66 | MYC (0.35) | ALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7291096 | 0.65 | HSD17B10 (0.46) | HTTALDH1A1MAPTALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |