Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7290643 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTTDP1HTR2A | |
| SCHEMBL7290637 | 0.89 | HTR2A (0.41) | ALDH1A1SMN1; SMN2HTTTDP1HTR2A | |
| SCHEMBL20265127 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTTDP1HTR2A | |
| SCHEMBL7287945 | 0.80 | PDE3B (0.49) | ALDH1A1HTTTDP1HTR2ASLC6A4 | |
| SCHEMBL7288619 | 0.79 | PDE4D (0.57) | HTTTDP1HTR2ASLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL7291531 | 0.79 | PDE3B (0.48) | ALDH1A1HTTTDP1HTR2ASLC6A4 | |
| SCHEMBL7269116 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTTCYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL7290566 | 0.77 | PDE4D (0.56) | HTTTDP1HTR2ASLC6A4HRH1 | |
| SCHEMBL7291597 | 0.76 | HTR3A (0.73) | ALDH1A1SMN1; SMN2TDP1HTR2ASLC6A4 | |
| SCHEMBL7290641 | 0.76 | HTT (0.39) | ALDH1A1SMN1; SMN2HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |