Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295284 | 1.00 | REN (0.53) | REN | |
| SCHEMBL7283971 | 0.90 | REN (0.42) | REN | |
| SCHEMBL7282601 | 0.90 | REN (0.42) | REN | |
| SCHEMBL9388134 | 0.89 | REN (0.52) | REN | |
| SCHEMBL7266011 | 0.89 | PSEN1 (0.49) | REN | |
| SCHEMBL7266006 | 0.89 | PSEN1 (0.49) | REN | |
| SCHEMBL7329529 | 0.89 | REN (0.50) | REN | |
| SCHEMBL9556804 | 0.88 | REN (0.41) | REN | |
| SCHEMBL7298963 | 0.88 | REN (0.41) | REN | |
| SCHEMBL7289817 | 0.88 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |