Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302831 | 1.00 | REN (0.41) | RENCTSDCTSE | |
| SCHEMBL9556796 | 1.00 | REN (0.41) | RENCTSDCTSE | |
| SCHEMBL7298963 | 1.00 | REN (0.41) | RENCTSDCTSE | |
| SCHEMBL7289817 | 1.00 | REN (0.41) | RENCTSDCTSE | |
| SCHEMBL9225629 | 0.91 | REN (0.40) | REN | |
| SCHEMBL7283971 | 0.91 | REN (0.42) | REN | |
| SCHEMBL7282601 | 0.91 | REN (0.42) | REN | |
| SCHEMBL7295284 | 0.88 | REN (0.53) | REN | |
| SCHEMBL7293156 | 0.88 | REN (0.53) | REN | |
| SCHEMBL7290037 | 0.86 | REN (0.40) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256645-A | Renin inhibitors; hypotensive agents | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |