Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.74 |
| ▸ | MMP1 | P03956 | 3/20 | 0.74 |
| ▸ | MMP2 | P08253 | 3/20 | 0.74 |
| ▸ | MMP8 | P22894 | 3/20 | 0.74 |
| ▸ | VIPR2 | P41587 | 16/20 | 0.63 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.59 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293187 | 1.00 | MMP9 (0.74) | MMP9MMP1MMP2MMP8VIPR2 | |
| SCHEMBL7300253 | 0.92 | VIPR2 (0.70) | MMP9MMP1MMP2MMP8VIPR2 | |
| SCHEMBL7300250 | 0.92 | VIPR2 (0.70) | MMP9MMP1MMP2MMP8VIPR2 | |
| SCHEMBL6466122 | 0.89 | VIPR2 (0.69) | MMP9MMP1MMP2MMP8VIPR2 | |
| SCHEMBL15713420 | 0.86 | VIPR2 (0.66) | MMP9VIPR2 | |
| SCHEMBL15714613 | 0.86 | VIPR2 (0.66) | MMP9VIPR2 | |
| SCHEMBL6046048 | 0.85 | MMP9 (1.00) | MMP9MMP1MMP2MMP8ADAMTS4 | |
| SCHEMBL6046057 | 0.85 | MMP9 (1.00) | MMP9MMP1MMP2MMP8ADAMTS4 | |
| SCHEMBL7293265 | 0.85 | VIPR2 (0.65) | MMP9MMP1MMP2MMP8VIPR2 | |
| SCHEMBL6469322 | 0.85 | VIPR2 (0.64) | MMP9MMP1MMP2MMP8VIPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480714-A2 | HIV protease inhibitors having symmetrical structure | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |