Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289919 | 0.88 | GPR3 (0.37) | GPR3PTGS1PTGS2CHRM5SCN1A | |
| SCHEMBL9586832 | 0.80 | RAB9A (0.41) | HPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL578279 | 0.80 | RAB9A (0.41) | HPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7297788 | 0.76 | MAPT (0.38) | KCNH2ALDH1A1RAB9A | |
| SCHEMBL9585550 | 0.73 | FABP6 (0.40) | HPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL577551 | 0.73 | FABP6 (0.40) | HPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7301082 | 0.72 | P2RY1 (0.36) | GPR3PTGS1PTGS2BACE1CTSD | |
| SCHEMBL7293216 | 0.70 | PTGS1 (0.41) | GPR3PTGS1PTGS2CHRM5SCN1A | |
| SCHEMBL30616492 | 0.70 | CTNNB1 (0.41) | GPR3PTGS1PTGS2CHRM5CA12 | |
| SCHEMBL17384160 | 0.70 | CTNNB1 (0.41) | GPR3PTGS1PTGS2CHRM5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |