Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297377 | 0.91 | F2 (0.50) | ACEF2PRCPFOLH1CTRB1 | |
| SCHEMBL7302872 | 0.90 | ACE (0.44) | ITGB3ITGA2BACEF2PRCP | |
| SCHEMBL7301590 | 0.86 | ACE (0.45) | ACEF2PRCPFOLH1CTRB1 | |
| SCHEMBL7304353 | 0.86 | ACE (0.49) | ACEF2PRCPFOLH1CTRB1 | |
| SCHEMBL7294739 | 0.85 | KMT2A (0.46) | ITGB3ITGA2BACEPRCPFOLH1 | |
| SCHEMBL7295927 | 0.81 | F2 (0.49) | ACEF2PRCPCTRB1KMT2A | |
| SCHEMBL7293940 | 0.81 | PTGER4 (0.52) | ITGB3ITGA2BACEF2PRCP | |
| SCHEMBL29388202 | 0.80 | PREP (0.51) | ACEF2PRCPFOLH1CTRB1 | |
| SCHEMBL10724980 | 0.80 | MALT1 (0.45) | ITGB3ITGA2BACEPRCPFOLH1 | |
| SCHEMBL7295726 | 0.80 | OPRM1 (0.44) | ACEF2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |