Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297377 | 0.91 | F2 (0.50) | ACEF2PRCPFOLH1DPP4 | |
| SCHEMBL7297974 | 0.90 | ACE (0.42) | ACEF2PRCPDPP4DPP8 | |
| SCHEMBL7304353 | 0.86 | ACE (0.49) | ACEF2PRCPFOLH1CTRB1 | |
| SCHEMBL7294033 | 0.86 | ITGB3 (0.49) | ACEF2PRCPFOLH1DPP4 | |
| SCHEMBL7294739 | 0.83 | KMT2A (0.46) | ACEPRCPFOLH1DPP4DPP8 | |
| SCHEMBL7295927 | 0.81 | F2 (0.49) | ACEF2PRCPDPP4DPP8 | |
| SCHEMBL7293940 | 0.78 | PTGER4 (0.52) | ACEF2PRCPFOLH1DPP4 | |
| SCHEMBL29388202 | 0.78 | PREP (0.51) | ACEF2PRCPFOLH1DPP4 | |
| SCHEMBL10724980 | 0.78 | MALT1 (0.45) | ACEPRCPFOLH1DPP4DPP8 | |
| SCHEMBL7295726 | 0.77 | OPRM1 (0.44) | ACEF2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |