Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292847 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS15F10 | |
| Hydrochloric Acid SCHEMBL9270486 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1TMPRSS15F10 | |
| SCHEMBL7282886 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1TMPRSS2F2 | |
| SCHEMBL7122825 | 0.85 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1F10TMPRSS2 | |
| SCHEMBL7291480 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1F10TMPRSS2 | |
| Hydrochloric Acid SCHEMBL9636418 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1TMPRSS15EPHX2 | |
| Hydrochloric Acid SCHEMBL9268803 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1TMPRSS15EPHX2 | |
| Hydrochloric Acid SCHEMBL8040370 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BPRSS1F10TMPRSS2 | |
| SCHEMBL8381464 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1F10TMPRSS2 | |
| SCHEMBL7303302 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1TMPRSS15EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |
| US-5399585-A | Anitcoagulants, antiinflammatory, antitumor | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5084466-A | Anticoagulants, antiinflammatory agents, atheriosclerosis and antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1992-01-28 | — | — | US | disclosed |