Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.63 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.59 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.59 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | S100B | P04271 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8040370 | 0.98 | ITGB3 (0.73) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL8410645 | 0.95 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL8407198 | 0.95 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL7291480 | 0.92 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL7282886 | 0.91 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Hydrochloric Acid SCHEMBL7832473 | 0.91 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Iodide SCHEMBL7829929 | 0.91 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Acetic Acid SCHEMBL8382531 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL7782353 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2BPRSS1F2ST14 | |
| SCHEMBL7294121 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
| US-6071917-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; ESPECIALLY FOR THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; COMPETITIVE BINDING AT RECEPTORS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-06-06 | — | — | US | disclosed |
| US-4018933-A | PENICILLINS; BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | ITGB3 292/4885ITGA2B 117/4885PRSS1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.