Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | F7 | P08709 | 4/20 | 0.53 |
| ▸ | F3 | P13726 | 4/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18350998 | 0.94 | PPARG (0.61) | PPARGALDH1A1PPARDPPARAKDM4E | |
| SCHEMBL17322184 | 0.94 | F7 (0.52) | PPARGALDH1A1PPARDPPARAKDM4E | |
| SCHEMBL7284959 | 0.94 | F7 (0.52) | PPARGALDH1A1PPARDPPARAKDM4E | |
| SCHEMBL7298676 | 0.92 | ALDH1A1 (0.62) | PPARGALDH1A1PPARDPPARAKDM4E | |
| SCHEMBL11857550 | 0.87 | FAAH (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL6641866 | 0.87 | FAAH (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL9614464 | 0.85 | FAAH (0.59) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL9614461 | 0.85 | FAAH (0.59) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL10563116 | 0.85 | FAAH (0.59) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL10905226 | 0.85 | FAAH (0.59) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |