SCHEMBL7294247

SCHEMBL7294247

O=C(CC1CCc2ccccc2C1)C1CCN[C@H]1C(=O)N1CCCC1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 19/20 0.57
UGCG Q16739 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153717 1.00 PREP (0.57) PREPUGCG
SCHEMBL8154403 1.00 PREP (0.57) PREPUGCG
SCHEMBL8155765 0.87 PREP (0.60) PREP
SCHEMBL8154287 0.87 PREP (0.60) PREP
SCHEMBL7295946 0.87 PREP (0.60) PREP
SCHEMBL9047189 0.85 PREP (0.48) PREP
SCHEMBL9791388 0.84 PREP (0.49) PREP
SCHEMBL7440061 0.84 CYP26A1 (0.44) PREPUGCG
SCHEMBL9047944 0.83 PREP (0.64) PREP
SCHEMBL8152373 0.83 PREP (0.64) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017929-A Cholinesterase activator ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0754454-A1 CHOLINESTERASE ACTIVATOR ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-01-22 EP disclosed
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed