Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 16/20 | 0.60 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295946 | 1.00 | PREP (0.60) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL8155765 | 1.00 | PREP (0.60) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7305077 | 0.90 | PREP (0.53) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL8153717 | 0.87 | PREP (0.57) | PREP | |
| SCHEMBL7294247 | 0.87 | PREP (0.57) | PREP | |
| SCHEMBL8154403 | 0.87 | PREP (0.57) | PREP | |
| SCHEMBL7294740 | 0.86 | DPP4 (0.46) | PREPDPP4DPP8DPP9 | |
| SCHEMBL7300891 | 0.84 | PREP (0.48) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7296688 | 0.84 | PREP (0.43) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7294365 | 0.83 | PREP (0.48) | PREPDPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |