SCHEMBL729426

SCHEMBL729426

C=CCN(CC=C)C(=O)C(=C)N

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.35
DPP4 P27487 2/20 0.35
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
POLB P06746 1/20 0.33
F2 P00734 1/20 0.31
KLK1 P06870 1/20 0.31
PRSS1 P07477 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4483932 0.83 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2DPP4TSHRFGFR4
SCHEMBL569156 0.82 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2DPP4TSHRPOLB
SCHEMBL16240025 0.79 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2DPP4GRIN2DGRIN3B
SCHEMBL1816811 0.77 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2DPP4POLB
SCHEMBL3652188 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2DPP4TSHRFGFR4
SCHEMBL569861 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2DPP4TSHRFGFR4
SCHEMBL11668092 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2DPP4POLBMAPT
SCHEMBL22986557 0.76 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2DPP4POLBMAPT
SCHEMBL21224872 0.76 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2DPP4POLBMAPT
SCHEMBL131046 0.76 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2DPP4POLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403537-B1 CATIONIC COPOLYMER OF ACRYLAMIDE MONOMERS AND QUATERNARY SALTS OF N,N-DIALKYLAMINOACRYLAMIDE, A BRIDGING AGENT TO BRIDGE THE PORES IN THE FORMATION; OPTIONALLY 2-AMINO-2-METHYLPROPANE SULFONIC ACID BAKER HUGHES INCORPORATED 2002-06-11 US claimed
WO-2000027944-B1 DRILLING FLUID SYSTEMS WITH IMPROVED FLUID LOSS PROPERTIES BAKER HUGHES INC (US) 2000-08-10 WO claimed
WO-2000027944-A1 DRILLING FLUID SYSTEMS WITH IMPROVED FLUID LOSS PROPERTIES BAKER HUGHES INCORPORATED (US) 2000-05-18 WO claimed
US-8136676-B2 a membrane or fibers composed of or coated with methoxyethyl methacrylate/2-/-di(ethylene glycol)ethyl ether methacrylate-2-(diethylamino)ethyl methacrylate terpolymer for the selective removal, reduction or separation of white blood cells and/or platelets from blood by passing blood through the medium UNIVERSITY OF SOUTHAMPTON (GB) 2012-03-20 US disclosed
US-20080190843-A1 Polymers Useful as Medical Materials UNIVERSITY OF SOUTHAMPTON (GB) 2008-08-14 US disclosed
US-6403537-B1 CATIONIC COPOLYMER OF ACRYLAMIDE MONOMERS AND QUATERNARY SALTS OF N,N-DIALKYLAMINOACRYLAMIDE, A BRIDGING AGENT TO BRIDGE THE PORES IN THE FORMATION; OPTIONALLY 2-AMINO-2-METHYLPROPANE SULFONIC ACID BAKER HUGHES INCORPORATED 2002-06-11 US disclosed