Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551757 | 0.88 | HCAR2 (0.44) | HCAR2KMT2AALDH1A1MAPTKLK7 | |
| SCHEMBL17508198 | 0.82 | ADRA2A (0.55) | HCAR2PTGDR2ADRA2AADRA2BADRA2C | |
| SCHEMBL30110816 | 0.82 | ADRA2A (0.55) | HCAR2PTGDR2ADRA2AADRA2BADRA2C | |
| SCHEMBL15058014 | 0.81 | KMT2A (0.46) | PTGDR2ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL8185048 | 0.81 | KMT2A (0.62) | PTGDR2ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL7294278 | 0.78 | HCAR2 (0.42) | HCAR2KMT2AGAAALDH1A1HPGD | |
| SCHEMBL11338676 | 0.77 | PTGDR2 (0.47) | PTGDR2ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL2558383 | 0.76 | KMT2A (0.47) | PTGDR2ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL15331058 | 0.74 | LMNA (0.50) | PTGDR2ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL6304130 | 0.74 | HCAR2 (0.50) | HCAR2PTGDR2KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |