Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7300839 | 0.85 | KDM4E (0.50) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3724624 | 0.83 | HTR3A (0.56) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3724622 | 0.83 | HTR3A (0.56) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7490360 | 0.83 | HTR3A (0.56) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL2318444 | 0.83 | HTR3A (0.56) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL7296594 | 0.82 | KDM4E (0.50) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL467193 | 0.82 | HTR3A (0.55) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12486470 | 0.81 | KDM4E (0.69) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| Iodomethane SCHEMBL1309118 | 0.81 | HTR3A (0.54) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9582122 | 0.78 | KDM4E (0.46) | KDM4EOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |