Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 15/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.48 |
| ▸ | HTR3B | O95264 | 6/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490360 | 1.00 | HTR3A (0.56) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL3724622 | 1.00 | HTR3A (0.56) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL2318444 | 1.00 | HTR3A (0.56) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL467193 | 0.99 | HTR3A (0.55) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| Iodomethane SCHEMBL1309118 | 0.97 | HTR3A (0.54) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL12486470 | 0.87 | KDM4E (0.69) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL7296594 | 0.84 | KDM4E (0.50) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL7297917 | 0.83 | KDM4E (0.52) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL7297920 | 0.83 | KDM4E (0.52) | HTR3AKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL7294608 | 0.83 | KDM4E (0.49) | HTR3AKDM4EOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087364-A1 | TROPINE MODULATORS OF 5-HT3 RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087364-A1 | TROPINE MODULATORS OF 5-HT3 RECEPTOR | HTR3A, HTR3B, HTR3E | HTR3A 1/4885KDM4E 3298/4885OPRM1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.