SCHEMBL7294685

SCHEMBL7294685

O=C(CC1=Cc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)N1CCSC1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 7/20 0.40
DPP4 P27487 12/20 0.39
FAP Q12884 1/20 0.39
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7303628 0.90 DPP4 (0.38) PREPDPP4FAPDPP8DPP9
SCHEMBL7301278 0.88 PREP (0.53) PREPDPP4FAP
SCHEMBL7292572 0.83 PREP (0.38) PREP
SCHEMBL7296683 0.81 PREP (0.52) PREPDPP4FAPDPP8DPP9
SCHEMBL9049089 0.80 PREP (0.35) PREPDPP4
SCHEMBL7295503 0.79 PREP (0.36) PREP
SCHEMBL7300887 0.79 PREP (0.46) PREPDPP4FAPDPP8DPP9
SCHEMBL7437369 0.78 DPP4 (0.30) DPP4FAP
SCHEMBL9050748 0.78 PREP (0.35) PREP
SCHEMBL7292862 0.78 PREP (0.47) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed