Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 7/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294685 | 0.90 | PREP (0.40) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL7437369 | 0.88 | DPP4 (0.30) | DPP4FAP | |
| SCHEMBL7303635 | 0.84 | DPP4 (0.39) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL7300887 | 0.82 | PREP (0.46) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL9047864 | 0.79 | PREP (0.41) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9048205 | 0.79 | PREP (0.41) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL7296683 | 0.78 | PREP (0.52) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL7305071 | 0.78 | PREP (0.51) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL7301278 | 0.78 | PREP (0.53) | DPP4FAPPREPHTR1AHTR2A | |
| SCHEMBL9049083 | 0.77 | PREP (0.41) | PREPHTR1AHTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |