Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292130 | 0.79 | TAAR1 (0.54) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL7290701 | 0.76 | TAAR1 (0.54) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL5633249 | 0.74 | PPARD (0.35) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL13372830 | 0.74 | TAAR1 (0.80) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL5633252 | 0.74 | PPARD (0.35) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL7289609 | 0.73 | TAAR1 (0.50) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL1507905 | 0.72 | TAAR1 (0.61) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8307737 | 0.71 | TAAR1 (0.59) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6323409 | 0.70 | TAAR1 (0.67) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6328191 | 0.69 | TAAR1 (0.56) | TAAR1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |