Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599591 | 0.83 | TAAR1 (0.62) | TAAR1CYP3A4CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL13372830 | 0.81 | TAAR1 (0.80) | TAAR1CYP2D6ALDH1A1HTR1AADRA2A | |
| SCHEMBL11706270 | 0.81 | TAAR1 (0.59) | TAAR1CYP3A4CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL11702483 | 0.81 | PLA2G2A (0.57) | TAAR1CYP3A4CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL10852193 | 0.79 | TAAR1 (0.57) | TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10621971 | 0.79 | TAAR1 (0.61) | TAAR1CYP2D6ALDH1A1HTR1ALTA4H | |
| SCHEMBL10674026 | 0.79 | TAAR1 (0.49) | TAAR1ALDH1A1HTR1AGAASMN1; SMN2 | |
| SCHEMBL10945831 | 0.78 | TAAR1 (0.51) | TAAR1ALDH1A1HTR1AGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10854378 | 0.78 | TAAR1 (0.55) | TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11477905 | 0.78 | TAAR1 (0.59) | TAAR1HTR1ALTA4HADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958353-B2 | Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts | HISAMITSU MEDICAL CO., LTD. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030207896-A1 | Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2003-11-06 | — | — | US | disclosed |
| EP-1295880-A1 | IMIDAZOLE DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE DERIVATIVES OR THE SALTS | SSP Co., Ltd. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207896-A1 | Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts | IL6, NOS1, NOS2 | TAAR1 1150/4885CYP3A4 80/4885CYP1A2 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.