Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897589 | 0.86 | HTR2A (0.63) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9971034 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL15345391 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL3277526 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL6856603 | 0.83 | MTNR1A (0.59) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL1012628 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL9056176 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| Bromide SCHEMBL29233693 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL5252235 | 0.81 | MEN1 (0.48) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL7193761 | 0.80 | MTNR1A (0.64) | MTNR1AMTNR1BSIGMAR1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826814-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | disclosed |