Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9272333 | 0.99 | EPHX2 (0.62) | EPHX2NR1H4ITGB3ITGA2BMEN1 | |
| SCHEMBL9452083 | 0.88 | EPHX2 (0.52) | EPHX2NR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL7295673 | 0.88 | MAPT (0.59) | EPHX2NR1H4ITGB3ITGA2BMEN1 | |
| Hydrochloric Acid SCHEMBL9270874 | 0.87 | EPHX2 (0.51) | EPHX2NR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL11787863 | 0.84 | ALDH1A1 (0.58) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL12801896 | 0.82 | EPHX2 (0.72) | EPHX2NR1H4ITGB3ITGA2BMEN1 | |
| SCHEMBL17894494 | 0.82 | HDAC1 (0.59) | EPHX2NR1H4MEN1KMT2AHPGD | |
| SCHEMBL11787869 | 0.82 | EPHX2 (0.56) | EPHX2NR1H4ITGB3ITGA2BMEN1 | |
| SCHEMBL7303517 | 0.81 | NR1H4 (0.61) | EPHX2NR1H4ITGB3ITGA2BITGB1 | |
| SCHEMBL7294446 | 0.81 | EPHX2 (0.52) | EPHX2NR1H4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |