Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.65 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296007 | 1.00 | REN (0.65) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9725876 | 0.89 | REN (0.61) | REN | |
| SCHEMBL9725871 | 0.89 | REN (0.61) | REN | |
| SCHEMBL7268440 | 0.83 | REN (0.49) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7268445 | 0.83 | REN (0.49) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7268437 | 0.83 | REN (0.49) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7269995 | 0.83 | REN (0.63) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9551232 | 0.81 | REN (0.73) | REN | |
| SCHEMBL9101385 | 0.81 | REN (0.73) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6897460 | 0.81 | REN (0.73) | RENPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |