Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SELL | P14151 | 2/20 | 0.48 |
| ▸ | SELP | P16109 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | FUT4 | P22083 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96645 | 0.71 | SELL (0.47) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL67497 | 0.69 | BACE1 (0.54) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL25183526 | 0.69 | SELL (0.53) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL11041875 | 0.69 | KDM4E (0.59) | LMNATDP1KDM4EALDH1A1SELL | |
| Gallic Acid SCHEMBL28279123 | 0.67 | CA12 (0.90) | LMNATDP1KDM4EALDH1A1SELL | |
| Gallic Acid SCHEMBL5421738 | 0.67 | CA12 (0.90) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL6873138 | 0.67 | HSD17B10 (0.58) | LMNAKDM4EALDH1A1MAPTCA1 | |
| SCHEMBL21845103 | 0.67 | KDM4E (0.50) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL352369 | 0.67 | KDM4E (0.65) | LMNATDP1KDM4EALDH1A1SELL | |
| SCHEMBL3123299 | 0.67 | CA1 (0.58) | LMNAKDM4EALDH1A1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |