Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286476 | 0.86 | SLC2A1 (0.61) | SLC2A1POLBHTR1AABCB1SMN1; SMN2 | |
| SCHEMBL10382981 | 0.86 | SLC2A1 (0.47) | SLC2A1POLBHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL10383913 | 0.85 | SLC2A1 (0.53) | SLC2A1MEN1KMT2AAPEX1TAAR1 | |
| SCHEMBL7285255 | 0.84 | SLC2A1 (0.47) | SLC2A1POLBPKMMEN1KMT2A | |
| SCHEMBL7273729 | 0.84 | SLC2A1 (0.52) | SLC2A1POLBABCB1SMN1; SMN2TAAR1 | |
| SCHEMBL7440335 | 0.82 | TUBB4A (0.50) | POLBKMT2AABCB1TUBB4ATUBB | |
| SCHEMBL7442211 | 0.81 | TUBB4A (0.55) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL7438719 | 0.81 | MEN1 (0.51) | SLC2A1POLBMEN1KMT2AHTR1A | |
| SCHEMBL7284175 | 0.80 | APEX1 (0.53) | SLC2A1POLBPKMMEN1KMT2A | |
| Methyl Alcohol SCHEMBL7431285 | 0.79 | ABCB1 (0.54) | POLBPKMHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |