Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296220 | 0.71 | CYP19A1 (0.38) | CYP19A1MAPT | |
| SCHEMBL7287644 | 0.70 | MEN1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL7980719 | 0.67 | CYP19A1 (0.46) | CYP19A1DDB1CRBN | |
| SCHEMBL3442854 | 0.64 | MEN1 (0.42) | CYP19A1DDB1CRBNALDH1A1MAPT | |
| SCHEMBL28863420 | 0.62 | DDB1 (0.41) | CYP19A1DDB1CRBNALDH1A1MAPT | |
| SCHEMBL20401811 | 0.62 | DDB1 (0.41) | CYP19A1DDB1CRBNALDH1A1MAPT | |
| SCHEMBL16701751 | 0.62 | CRBN (0.54) | CYP19A1DDB1CRBNALDH1A1 | |
| SCHEMBL31016082 | 0.61 | CYP19A1 (0.52) | CYP19A1DDB1CRBNALDH1A1MAPT | |
| SCHEMBL2756388 | 0.59 | DDB1 (0.39) | CYP19A1DDB1CRBNALDH1A1MAPT | |
| SCHEMBL19675259 | 0.59 | PARP3 (0.39) | CYP19A1DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383449-B1 | Pyridazinone derivatives and processes for preparing the same | ORION YHTYMAE OY (FI) | 1995-09-06 | — | — | EP | disclosed |
| US-5122524-A | Treatment for congestive heart failure; hypertensive agents; vasodilation | ORION-YHTYMA OY (FI) | 1992-06-16 | — | — | US | disclosed |
| US-5019575-A | Congestive Heart Failure Treatment | ORION-YHTYMA OY (FI) | 1991-05-28 | — | — | US | disclosed |
| EP-0383449-A2 | Pyridazinone derivatives and processes for preparing the same | ORION-YHTYMÀ OY (FI) | 1990-08-22 | — | — | EP | disclosed |