Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091735 | 0.70 | SLC6A3 (0.40) | CYP3A4 | |
| SCHEMBL5179397 | 0.69 | SMN1; SMN2 (0.43) | DDB1CRBN | |
| SCHEMBL10373571 | 0.69 | CYP19A1 (0.44) | CYP19A1DDB1CRBN | |
| SCHEMBL16701751 | 0.67 | CRBN (0.54) | CYP19A1DDB1CRBNTBXAS1PDE4D | |
| SCHEMBL7296137 | 0.67 | CYP19A1 (0.38) | CYP19A1DDB1CRBN | |
| SCHEMBL8993494 | 0.67 | ALDH1A1 (0.38) | DDB1CRBN | |
| SCHEMBL1859440 | 0.66 | CYP19A1 (0.61) | CYP19A1DDB1CRBNGSK3BBACE1 | |
| SCHEMBL3442854 | 0.65 | MEN1 (0.42) | CYP19A1DDB1CRBNCYP3A4 | |
| SCHEMBL28863420 | 0.63 | DDB1 (0.41) | CYP19A1DDB1CRBNCYP3A4 | |
| SCHEMBL20401811 | 0.63 | DDB1 (0.41) | CYP19A1DDB1CRBNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000598-A1 | N-[4-(6-OXOTETRAHYDROTRIAZINYL)PHENYL]AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | claimed |
| WO-2001000598-A1 | N-[4-(6-OXOTETRAHYDROTRIAZINYL)PHENYL]AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000598-A1 | N-[4-(6-OXOTETRAHYDROTRIAZINYL)PHENYL]AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |