Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.86 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.72 |
| ▸ | QPCT | Q16769 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | NOS1 | P29475 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303484 | 0.93 | TBXAS1 (1.00) | TBXAS1CACNA1BMEN1KMT2AL3MBTL1 | |
| SCHEMBL7873899 | 0.88 | TBXAS1 (0.72) | TBXAS1CACNA1BQPCTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2529362 | 0.88 | MEN1 (0.85) | TBXAS1QPCTMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7875269 | 0.87 | TBXAS1 (0.70) | TBXAS1CACNA1BQPCTMEN1KMT2A | |
| SCHEMBL8995361 | 0.85 | QPCT (0.69) | TBXAS1QPCTMEN1KMT2AATM | |
| SCHEMBL688957 | 0.85 | TBXAS1 (0.88) | TBXAS1QPCTKMT2ANOS1 | |
| SCHEMBL6302835 | 0.82 | QPCT (0.73) | TBXAS1QPCTMEN1KMT2AATM | |
| SCHEMBL10457427 | 0.82 | QPCT (0.73) | TBXAS1QPCTMEN1KMT2AATM | |
| SCHEMBL8684902 | 0.82 | QPCT (0.73) | TBXAS1CACNA1BQPCTMEN1KMT2A | |
| SCHEMBL12834989 | 0.82 | QPCT (1.00) | TBXAS1QPCTMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |