Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225350 | 0.87 | TSHR (0.54) | HPGDPOLBTSHRALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL7298291 | 0.86 | TSHR (0.53) | HPGDPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL8701236 | 0.83 | HPGD (0.55) | HPGDPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL7292745 | 0.79 | PREP (0.49) | TSHRALDH1A1MAPTPREPKMT2A | |
| SCHEMBL7338507 | 0.74 | ALDH1A1 (0.48) | HPGDPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL6786668 | 0.72 | KLK5 (0.46) | ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6786659 | 0.72 | KLK5 (0.46) | ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6783713 | 0.72 | NPC1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL6783707 | 0.72 | NPC1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL13590682 | 0.72 | HPGD (0.64) | HPGDPOLBTSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380713-A | Serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-10 | — | — | US | claimed |
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |
| US-5380713-A | Serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |