Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225350 | 0.88 | TSHR (0.54) | HPGDTSHRALOX15ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7298291 | 0.87 | TSHR (0.53) | HPGDTSHRALOX15ALDH1A1MAPT | |
| SCHEMBL7296629 | 0.83 | HPGD (0.49) | HPGDTSHRALOX15ALDH1A1MAPT | |
| SCHEMBL7338507 | 0.82 | ALDH1A1 (0.48) | HPGDTSHRALOX15ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7293117 | 0.76 | GAA (0.42) | HPGDTSHRALOX15ALDH1A1MAPT | |
| SCHEMBL8696363 | 0.76 | F2 (0.56) | ALDH1A1LMNAHTT | |
| SCHEMBL8701245 | 0.74 | TSHR (0.52) | HPGDTSHRALOX15ALDH1A1MAPT | |
| SCHEMBL7468069 | 0.74 | PPARG (0.64) | TSHRALOX15ALDH1A1POLBHTT | |
| SCHEMBL5622664 | 0.73 | SMN1; SMN2 (0.64) | TSHRALOX15ALDH1A1POLBHTT | |
| SCHEMBL8654838 | 0.72 | PREP (0.71) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |