Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.77 |
| ▸ | NPC1 | O15118 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.77 |
| ▸ | TP53 | P04637 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | PLAU | P00749 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680508 | 0.90 | NPC1 (0.93) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL7243018 | 0.87 | NR1H4 (0.72) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL4248077 | 0.87 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL4254168 | 0.87 | TP53 (0.80) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL7301192 | 0.86 | NPC1 (0.81) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL7304276 | 0.86 | NPC1 (0.81) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL29420092 | 0.84 | NPC1 (0.81) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL1918108 | 0.84 | NPC1 (0.81) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL5224977 | 0.83 | NR1H4 (0.69) | NPC1RAB9ATP53KMT2AMEN1 | |
| SCHEMBL12218147 | 0.83 | RAB9A (0.79) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |