SCHEMBL7297239

SCHEMBL7297239

CC(C)(C)c1ccc(C(=O)Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 5/20 0.81
EPHX2 P34913 1/20 0.81
HDAC3 O15379 1/20 0.75
HDAC11 Q96DB2 1/20 0.75
HDAC8 Q9BY41 1/20 0.75
HDAC6 Q9UBN7 1/20 0.75
TRPV1 Q8NER1 5/20 0.73
NPC1 O15118 2/20 0.73
RAB9A P51151 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
MEN1 O00255 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
KMT2A Q03164 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
SRD5A2 P31213 1/20 0.65
KCNK9 Q9NPC2 1/20 0.64
MITF O75030 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3873116 1.00 NR1H4 (0.81) NR1H4EPHX2HDAC3HDAC11HDAC8
SCHEMBL7303163 0.93 HDAC3 (0.86) NR1H4HDAC3HDAC11HDAC8HDAC6
SCHEMBL5697470 0.91 NR1H4 (0.68) NR1H4EPHX2HDAC3HDAC11HDAC8
SCHEMBL22059470 0.89 NR1H4 (1.00) NR1H4EPHX2HDAC3HDAC11HDAC8
SCHEMBL8460187 0.88 HDAC6 (0.75) NR1H4EPHX2HDAC3HDAC11HDAC8
SCHEMBL4250752 0.87 KCNK9 (0.81) NR1H4HDAC3HDAC11HDAC8HDAC6
SCHEMBL7302565 0.87 KCNK9 (0.76) NR1H4HDAC3HDAC11HDAC8HDAC6
SCHEMBL900903 0.87 MITF (0.81) HDAC8HDAC6NPC1RAB9AMEN1
SCHEMBL28419632 0.87 MITF (0.81) HDAC8HDAC6NPC1RAB9AMEN1
SCHEMBL8827340 0.87 MITF (0.81) HDAC8HDAC6NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333593-A1 Fire Resistant Two-Part System ZEPHYROS INC (US) 2025-10-30 US disclosed
US-12139637-B2 Flame retardant vapor retarding membranes CERTAINTEED LLC (US) 2024-11-12 US disclosed
EP-4402211-A1 FIRE RESISTANT TWO-PART SYSTEM Zephyros, Inc. (US) 2024-07-24 EP disclosed
CN-117940509-A Fire resistant two part system 泽菲罗斯有限公司 2024-04-26 CN disclosed
US-11795684-B2 Vapor retarding building materials and methods for making them CERTAINTEED LLC (US) 2023-10-24 US disclosed
WO-2023043930-A1 FIRE RESISTANT TWO-PART SYSTEM ZEPHYROS, INC. (US) 2023-03-23 WO disclosed
US-20220154011-A1 FLAME RETARDANT VAPOR RETARDING MEMBRANES CERTAINTEED LLC 2022-05-19 US disclosed
US-20220098853-A1 VAPOR RETARDING BUILDING MATERIALS AND METHODS FOR MAKING THEM CERTAINTEED LLC 2022-03-31 US disclosed
US-11236237-B2 Flame retardant vapor retarding membranes CERTAINTEED LLC (US) 2022-02-01 US disclosed
WO-1999048529-A1 RETINOID-GLITAZONE COMBINATIONS WARNER-LAMBERT COMPANY (US) 1999-09-30 WO disclosed
WO-1998025949-A1 SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES PROSCRIPT, INC. (US) 1998-06-18 WO disclosed
EP-0808159-A1 USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) WARNER-LAMBERT COMPANY (US) 1997-11-26 EP disclosed
WO-1996024344-A1 USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) WARNER-LAMBERT COMPANY (US) 1996-08-15 WO disclosed
US-5489611-A ADMINISTERING A RETINOID COMPOUND WARNER-LAMBERT COMPANY (US) 1996-02-06 US disclosed
EP-0358118-B1 Phenylamides - process for their preparation as well as a drug containing those compounds BOEHRINGER MANNHEIM GMBH (DE) 1994-03-16 EP disclosed
US-5135949-A Anticoagulants BOEHRINGER MANNHEIM GMBH (DE) 1992-08-04 US disclosed
EP-0358118-A1 Phenylamides - process for their preparation as well as a drug containing those compounds Roche Diagnostics GmbH (DE) 1990-03-14 EP disclosed