Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25400526 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL7299402 | 0.81 | KDM4E (0.56) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL13940123 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL762893 | 0.77 | KMT2A (0.56) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL17040325 | 0.77 | ATM (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL25399680 | 0.75 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL25406586 | 0.75 | TSHR (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL25409819 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL17037432 | 0.73 | ATM (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL7718402 | 0.73 | KDM4E (0.52) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-A2 | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |