Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298281 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL762893 | 0.78 | KMT2A (0.56) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL13957361 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL2805013 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL25399698 | 0.74 | MAPT (0.57) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL2291662 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL3713718 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7319949 | 0.73 | TSHR (0.52) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL1338456 | 0.73 | L3MBTL1 (0.61) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| Hydrochloric Acid SCHEMBL25401492 | 0.73 | MAPT (0.55) | KDM4EALDH1A1HPGDHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-B1 | BENZIMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4925854-A | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0304789-A2 | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |