Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530880 | 0.91 | ADORA3 (0.50) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL10556121 | 0.84 | ADORA3 (0.55) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL7322941 | 0.83 | ADORA3 (0.58) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL9359378 | 0.74 | ADORA3 (0.47) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL10502793 | 0.73 | ADORA3 (0.40) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL9690795 | 0.72 | KDM4E (0.45) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL11344156 | 0.72 | ADORA3 (0.48) | ADORA3KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL11005887 | 0.72 | CACNA1B (0.49) | ADORA3MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL11335061 | 0.71 | ADORA3 (0.45) | ADORA3KDM4EGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10872279 | 0.71 | SMN1; SMN2 (0.50) | ADORA3KDM4EGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308785-B1 | DIHYDROPYRIDINE ETHERS, PROCESSES FOR THEIR PREPARATION AND THEIR UTILISATION | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0308785-A2 | Dihydropyridine ethers, processes for their preparation and their utilisation | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |