Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290538 | 0.81 | HTR2C (0.33) | HTR2C | |
| SCHEMBL7299115 | 0.79 | PKM (0.32) | — | |
| SCHEMBL7300100 | 0.79 | — | — | |
| SCHEMBL7298538 | 0.77 | KDM4E (0.33) | HTR2C | |
| SCHEMBL7298521 | 0.76 | KMT2A (0.32) | HTR2CHTR2B | |
| SCHEMBL7290802 | 0.72 | PKM (0.33) | HTR2CHTR2BAHR | |
| SCHEMBL7290527 | 0.72 | P2RY1 (0.34) | — | |
| SCHEMBL23423307 | 0.67 | KDM1A (0.39) | HTR2CHTR2B | |
| SCHEMBL7294563 | 0.67 | AHR (0.36) | HTR2CAHR | |
| SCHEMBL7298699 | 0.67 | HTR2C (0.42) | HTR2CHTR2BAHRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |